Dynamic atroposelective resolution of chiral salts derived from oily racemic nicotinamides and enantiopure dibenzoyltartaric acid (DBTA) was achieved by crystallization.The absolute structures of the axial chiral nicotinamides were determined by X-ray structural analysis.The chirality could be Stationery controlled by the selection of enantiopure D
FasL and FADD delivery by a glioma-specific and cell cycle-dependent HSV-1 amplicon virus enhanced apoptosis in primary human brain tumors
Abstract Background Glioblastoma multiforme is the most malignant cancer of the brain and is notoriously difficult to treat due to the highly proliferative and infiltrative nature of the cells.Herein, we explored the combination treatment of pre-established human glioma xenograft using multiple therapeutic genes whereby the gene expression is regul
Blunt abdominal injury resulting in a belly full of candy after a motocross accident, a case report
Abstract Background Blunt traumatic gastric perforations in children are rare.Delayed diagnosis will lead to abdominal contamination and may result in morbidity and even mortality.We present a case of an adolescent who sustained blunt abdominal injury in a motocross accident and presented with remarkable hyperdense spherical shaped structures on th